A TAILORED THERMOSENSITIVE PLGA-PEG-PLGA/EMULSOMES COMPOSITE FOR ENHANCED OXCARBAZEPINE BRAIN DELIVERY VIA THE NASAL ROUTE

A Tailored Thermosensitive PLGA-PEG-PLGA/Emulsomes Composite for Enhanced Oxcarbazepine Brain Delivery via the Nasal Route

The use of nanocarrier delivery systems for direct nose to brain drug delivery shows promise for achieving increased brain drug levels as compared to simple solution systems.An example of such nanocarriers is emulsomes formed Underarm Scrub from lipid cores surrounded and stabilised by a corona of phospholipids (PC) and a coating of Tween 80, which

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Conjoined subjects and verbal agreement resolution in Akebu

The paper deals with conjoined subjects and verbal agreement resolution in Akebu Nail Polish and contributes to the typology of noun phrase coordination and agreement resolution in Niger-Congo.Akebu demonstrates both inclusory and compositional coordination with pronominal conjuncts, the former being typical for animate conjuncts, the latter being

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A Forensically Sound Adversary Model for Mobile Devices.

In this paper, we propose an adversary model to facilitate forensic investigations of mobile devices (e.g.Android, iOS and Windows smartphones) that can be readily adapted to the latest mobile device technologies.This is essential given the ongoing and rapidly changing nature of mobile device technologies.An integral principle and significant const

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Numb positively regulates Hedgehog signaling at the ciliary pocket

Abstract Hedgehog (Hh) signaling relies on the primary cilium, a cell surface organelle that serves as a signaling hub for the cell.Using proximity labeling and quantitative proteomics, we identify Numb as a ciliary protein that positively regulates Hh signaling.Numb localizes to the ciliary pocket and acts as an endocytic adaptor to incorporate Pt

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